

Other physical and psychological symptoms are commonly experienced by patients with FND but may not be present. Some patients with FND may experience substantial or even complete remission followed by sudden relapses of symptoms. Symptoms often fluctuate and may vary from day to day or be present all the time.

Encouraging studies support the potential reversibility of FND with specifically tailored treatments. However, it is now established that FND is a common cause of disability and distress, which may overlap with other problems such as chronic pain and fatigue.

This had led, historically, to the condition being relatively neglected by both clinicians and researchers. Conventional tests such as MRI brain scans and EEGs are usually normal in patients with FND. FND can encompass a wide variety of neurological symptoms, such as limb weakness or seizures.įND is a condition at the interface between the specialties of neurology and psychiatry. 5 Myths About Orphan Drugs and the Orphan Drug Actįunctional neurological disorder (FND) is a medical condition in which there is a problem with the functioning of the nervous system and how the brain and body sends and/or receives signals, rather than a structural disease process such as multiple sclerosis or stroke.Information on Clinical Trials and Research Studies.New York, N.Y.: McGraw-Hill Education 2015. Harrison's Principles of Internal Medicine. American Academy of Orthopaedic Surgeons.Elk Grove Village, Ill.: American Academy of Pediatrics 2015. In: Pediatric Telephone Protocols: Office Version 15th ed. American College of Emergency Physicians.

Dizziness: Approach to evaluation and management. Zitelli and Davis' Atlas of Pediatric Physical Diagnosis. Rochester, Minn.: Mayo Foundation for Medical Education and Research 2017. Philadelphia, Pa.: Saunders Elsevier 2016. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. Emergency Medicine Clinics of North America. Rosen's Emergency Medicine: Concepts and Clinical Practice.
